Should you use niacinamide before or after acid?

Author: Gerardo Willms DVM  |  Last update: Friday, October 31, 2025

As a rule, it's usually best to apply your acid product first, then niacinamide. In some cases, the order may also depend on the product textures.

What is the correct order of serums?

Thin to Thick: Layer by lightest to thickest consistency. Many serums have a similar viscous consistency, but if you notice one is thicker, start with the thinner formula first. Take Your Time: Give each serum several seconds to set before moving onto the next.

Which one to apply first, hyaluronic acid or niacinamide?

When used together, always go with applying hyaluronic acid first, followed by Niacinamide. By following this, you would be able to attract plenty of hydration first. After that, apply Niacinamide to help regulate sebum production and help with the minimization of pores.

What order do you put niacinamide acid in?

Niacinamide and hyaluronic acid can make a powerful pair. If you're using a facial serum like our CeraVe Hydrating Hyaluronic Acid Serum, layer the serum directly onto clean skin before applying your niacinamide product in the next layer.

What not to pair with niacinamide?

Niacinamide generally works well with most products, but it's best not to combine it with vitamin C (ascorbic acid) in the same routine as it can cause irritation. Additionally, avoid using it with strong exfoliants or retinoids in high concentrations to prevent skin sensitivity. For more, check out my Quora Profile.

Why The Ordinary's Niacinamide 10% + Zinc 1% is Breaking You Out!

What cancels out niacinamide?

Niacinamide and vitamin C

This combination sparks a lot of debate among skincare experts. Some say that since both niacinamide and vitamin C contain antioxidants, they cancel each other out and might even lead to irritation.

What reacts badly with niacinamide?

Niacinamide works well with other skincare ingredients, including retinol and hyaluronic acid. However, some ingredients, like vitamin C, may interact negatively with niacinamide. Therefore, it's recommended to use products containing these ingredients at different times of the day or on alternate days.

Do you use acid before or after niacinamide?

In general, niacinamide makes the most sense towards the end of your routine, after you've applied any acids or other active ingredient-based serums. If using it in the daytime, make sure to apply sunscreen afterward.

Is 10% niacinamide too much?

For general skin tone correction, a niacinamide concentration between 4-5% is often effective and well-tolerated by most individuals. For those looking to tackle more pronounced hyperpigmentation, a higher concentration of 10% may be beneficial, though it's important to monitor the skin for any signs of irritation.

What step in routine should I use niacinamide?

It's suitable for all skin types and fits easily into your existing skincare routine. As for when to use niacinamide serum, we typically recommend applying products in order of consistency. That means your serum should come after toner, but before richer lotions or creams.

How long to wait between hyaluronic acid and niacinamide?

Hyaluronic acid serums are usually lightweight and absorb quickly, so you don't need to wait longer than a minute or two to apply a niacinamide cream. If both products are thick or sticky, wait until the skin absorbs the first layer to avoid mixing and diluting the products.

In what order should I use my ordinary products?

How To Build A Skincare Routine With The Ordinary Products
  1. Cleanser. Cleansing should always be the first step in your routine. ...
  2. Exfoliator. Once you've cleansed your skin in the morning, exfoliating should be next. ...
  3. Hydration serum. ...
  4. Eye serum. ...
  5. Antioxidant serum. ...
  6. Moisturiser. ...
  7. SPF. ...
  8. Cleanser.

Do you put retinol or niacinamide first?

It is not unusual to find a combination of niacinamide and retinol in a single skincare product, but you can use niacinamide and retinol as separate steps in a consistent routine. If you're using separate products, it is recommended that you apply retinol first then move forward with niacinamide application.

Which serum goes first, hyaluronic acid or niacinamide?

Hyaluronic acid and Niacinamide are a great pair as both are water-based treatments. When used together, always go with applying hyaluronic acid first, followed by Niacinamide.

Do you put serums or acids first?

And for those clogged pores and inflamed bumps, dot on salicylic acid (use these ingredients one at a time to avoid irritation). A good rule of thumb, is to apply them after your serums and before your moisturizer.

How to use the ordinary hyaluronic acid and niacinamide together?

3. When layering, apply hyaluronic acid before niacinamide. Fiction. Our lab recommends that water-based serums be applied in the order of your skin concerns.

What not to mix niacinamide with?

DON'T MIX: AHA/BHA and niacinamide

Niacinamide is used to treat hyperpigmentation and reduce fine lines and wrinkles, while alpha hydroxy acids (AHAs) and beta hydroxy acids (BHAs) are chemical exfoliants. To understand why niacinamide shouldn't be mixed with AHAs and BHAs, you need to consider pH.

Which is better, 5% or 10% niacinamide?

As the percentages suggest, 10% niacinamide contains a higher concentration and strength than 5%. With twice the concentration of their 5% counterparts, 10% niacinamide products offer enhanced delivery of nutrients to skin cells.

Which moisturizer is best after niacinamide serum?

Consider pairing your niacinamide face serum with hyaluronic acid for an enhanced skincare regimen. Combining niacinamide with hyaluronic acid can brighten, hydrate, and plump up your skin. Apply niacinamide serum on a cleansed skin and let it absorb. After a few seconds, follow up with hyaluronic acid face serum.

Is hyaluronic acid better in AM or PM?

If you have dehydrated skin, use hyaluronic acid serum both in the morning and at night. In the morning, it might help hydrate your skin and prepare it for the day ahead. At night, it might help repair and rejuvenate your skin while you sleep. Be sure to follow up with a moisturizer to lock in the hydration.

Which serum should I put on first?

As a general rule, serums should be applied from thinnest to thickest consistency. Thin formulas are lighter and have a smaller particle size, which means they can penetrate the skin faster and deeper. By applying them first, you're not hindering their efficacy and slowing down their absorption rate.

How to know if niacinamide is working?

Niacinamide and hyaluronic acid

While you may not see any significant results during the first few weeks, there should be a notable difference by about 4 weeks. After 8 weeks, you should notice more hydrated, smoother, and toned skin.

Why is my skin getting darker after using niacinamide?

Some may also have skin discoloration due to using niacinamide combined with other active ingredients that are too harsh for your skin type. Niacinamide can also cause problems when it's mixed with the following substances: Acids, including lactic acid, glycolic acid, and azelaic acid.

What compliments niacinamide?

Check out the list of ingredients that positively combine with niacinamide to benefit your skin effectively:
  • Niacinamide and vitamin C. ...
  • Niacinamide and retinol. ...
  • Niacinamide and salicylic acid. ...
  • Niacinamide and hyaluronic acid. ...
  • Niacinamide and Centella Asiatica.

Which acid Cannot be used with niacinamide?

There are several active ingredients that can be paired together and are beneficial for your skin. However, glycolic acid and niacinamide cannot be used together at the same time. This is because mixing these two ingredients can make these acids less effective.

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