Resveratrol is known to protect the skin from free radicals and helps interrupt and rebuff environmental stressors, whilst retinol helps with already present skincare issues; enlarged pores, uneven skin texture and fine lines.
Retin A and resveratrol are very different compounds. Retin A (tretinoin) is a drug. It's a form of vitamin A that is applied to the skin to treat acne or smooth fine lines. Resveratrol is an anti-inflammatory compound found in many foods.
Can I use resveratrol with other active ingredients like retinol, AHAs/BHAs, or vitamin C? In general, resveratrol can be used with active ingredients and actually works well with them, especially antioxidant-rich ones like vitamin C.
As previously mentioned, resveratrol can have a two-fold effect, both neutralizing free radicals and boosting antioxidant levels, so your skin can better defend and repair itself. One 2014 study found that topically applying resveratrol significantly improved fine lines, wrinkles, and elasticity in 12 weeks.
The same goes for rosehip oil, another ingredient that claims to rival retinol. “The amount of vitamin A found in most rosehip oils won't be enough to have the same effect on your skin as retinol,” says Dr. Gohara.
It's suited to anyone with a normal to dry skin type. SkinMedica Retinol Complex is another highly rated option. It comes in three strengths — 0.25 percent, 0.5 percent, and 1 percent — so you can gradually move up if needed.
Resveratrol and CR exhibited similar anti-aging activities both in vitro and in vivo, evidenced by their ability to inhibit AAPH-induced senescence and apoptosis, restore the age-related cognitive impairment caused by D-gal administration.
It's such a powerful antioxidant that it works even better than vitamin E and vitamin C when it comes to fighting off existing free radicals and preventing the formation of new free radicals.
It may also decrease pain and swelling, reduce levels of sugar in the blood, and help the body fight against disease. Resveratrol is most commonly used for high cholesterol, cancer, heart disease, and many other conditions. But there is no strong evidence to support resveratrol for any use.
It has been shown that formulations with resveratrol can stimulate the proliferation of fibroblasts and contributing to the increase in the concentration of collagen III.
Resveratrol does not appear to have side effects at short-term doses (1.0 g). Otherwise, at doses of 2.5 g or more per day, side effects may occurs, like nausea, vomiting, diarrhea and liver dysfunction in patients with non-alcoholic fatty liver disease [140].
Resveratrol is inactivated by the sun and doesn't do well in the morning, Hooper says. “If you have time [and the budget], applying multiple antioxidants is a good idea, as a variety offers more well-rounded protection.
A more straightforward approach is to use a collagen powder supplement enriched with hyaluronic acid and resveratrol like Body Kitchen Youthful Beauty Collagen Powder. Each serving contains 20 grams of real food, high-quality grass-fed and marine collagen that the body can easily absorb.
Using niacinamide before retinol works well. So does combining them into one product. A 2016 study found that a product containing retinol, niacinamide, hexylresorcinol, and resveratrol improved fine lines, sallowness, wrinkling, hyperpigmentation, and skin tone.
Patients who have blood disorders, which can cause bleeding, should be monitored by a physician while taking this product. People undergoing surgery should stop taking resveratrol two weeks before the surgery and not take it for two weeks after the surgery to reduce the risk of bleeding.
Studies prove its worth: A 2010 study showed that resveratrol fights against the free radical molecules that create the effects of aging in skin. Another 2014 study put this notion into action and found that applying resveratrol topically significantly improved fine lines, wrinkles, and elasticity in just 12 weeks.
Conclusion: The skin product combination of resveratrol, green tea polyphenols, and caffeine safely reduces facial redness in most patients by 6 weeks of continuous treatment and may provide further improvement with additional treatment.
An exciting study conducted by researchers at the University of Exeter and the University of Brighton have found that exposing senescent (aged) cells to resveratrol made the cells not only look younger, but behave like younger cells.
Overall, the current meta-analysis demonstrated that resveratrol intake significantly reduced weight, BMI, WC and fat mass, and significantly increased lean mass, but did not affect leptin and adiponectin levels.
Owing to its vascular-enhancing properties, resveratrol may be effective in the microcirculation of the eye, thereby helping prevent ocular diseases such as age-related macular degeneration, diabetic retinopathy, and glaucoma.
Retinoids reduce fine lines and wrinkles by increasing the production of collagen. They also stimulate the production of new blood vessels in the skin, which improves skin color. Additional benefits include fading age spots and softening rough patches of skin.
First, the answer is yes, retinol can make wrinkles worse, especially when you first start using it. What is happening is a drying effect, and one can get epidermal sliding from separation from the dermis.
Retinoids work best if you use them daily. Specifically, they should be used at night because some types are deactivated by light and air. It's important to start slowly and allow your skin time to adjust. Using too much too quickly can cause redness, dryness, and irritation.