Prescription retinoids are stronger and may be more effective than their OTC counterparts at reducing the appearance of fine lines and wrinkles. This means they're also more likely to cause side effects.
Both retinol and retinoids can help keep acne from forming. The difference is that retinoids, like Retin-A, are prescription medications that have been FDA-approved to treat acne, while retinol is found in numerous OTC skin care products.
Retinols and retinoids are born of the same vitamin; but retinoids are more potent and are classified as a pharmaceutical, meaning you need a prescription to use a retinoid cream. Although recently, an over the counter retinoid (adapalene 0.1% gel) has become available without a prescription.
Prescription retinoid is available in a variety of strengths: 0.018%, 0.025% and 0.05% w/w. Whilst these seem like minuscule amounts, prescription retinoid is quite potent. It's best to start on a lower strength and increase it if your skin tolerates the concentration.
For aging skin, dermatologists like to prescribe tretinoin and retinoic acid (Retin-A, Renova, Refissa) that is "100 times" as potent as the retinol-containing products sold without prescription, Jacob says. "Tretinoin works better because it has a stronger capability of preventing the breakdown of collagen," she says.
On average, it takes eight to 24 weeks of treatment for tretinoin to produce noticeable improvements in wrinkles and other signs of aging. One short study published in the Journal of Cosmetic Dermatology, which used a . 025 percent tretinoin cream, found a “statistically significant improvement” after just 84 days.
For the purposes of skin care, tretinoin can be thought of as a more concentrated version of retinol. This means that tretinoin is stronger than retinol. This difference in strength can help guide your decision-making when it comes to choosing a skin care product. Your skin is affected by more than what you put on it.
High-strength retinol – 0.3%-1%
Those with stubborn skin concerns, like deep wrinkles and pronounced uneven skin tone may want to consider a high percentage retinol cream, serum or treatment. Look for those with a retinol percentage of between 0.3% and 1%.
You'll likely want to use retinol once or twice per week initially and work up to using it more than that. The reason: Retinol can initially be drying, especially if you have sensitive skin, so it's a good idea to give your skin some time to adjust to the change in your routine.
Physicians can legally prescribe a drug for any use. But the high-profile FDA-Ortho tussle has left some doctors hesitant to prescribe Retin-A for sun-damaged skin and has resurrected questions about its effectiveness.
In general, retinoids are stronger than retinol. They contain a higher concentration of the product, and the molecular structure of vitamin A in this form allows it to turn over skin cells at a faster rate than retinol.
The Drunk Elephant A-Passioni Retinol Cream formula contains a strong 1% concentration of retinol, which is one of the highest concentrations you can get over-the-counter.
If your dermatologist recommends retinol or another retinoid, request a prescription. Then, use RxSaver to look for the pharmacy with the best pricing and have your prescription filled at that location. This may help you save up to 80% on the medication.
While Vitamin C serum predominantly protects your skin from damage, retinol serum actively heals the damage on your skin. Vitamin C serum protects the collagens while the Retinol serum helps in cell turn over thereby creating new collagens.
Should you use retinol under your eyes? Yes, definitely. While it is true that retinol – a form of vitamin A – is a powerful ingredient and the skin under your eyes is delicate, there's no reason why you should miss out on the amazing benefits of retinol.
First, the answer is yes, retinol can make wrinkles worse, especially when you first start using it. What is happening is a drying effect, and one can get epidermal sliding from separation from the dermis.
“Studies suggest you need to use at least 0.25% retinol or 0.025% tretinoin to be effective, so I recommend using a product that specifies the percentage,” Dr. Rogers explains. When choosing a retinol product for the first time, it's best to start with the lowest concentration before moving up.
While prescription-strength retinoids may have an effect in a matter of weeks, it can take up to 6 months for OTC retinols to produce the same results. You may notice a difference in conditions like acne after 12 weeks, but sun damage and signs of aging can take much, much longer to improve.
Tretinoin gel, cream, or lotion requires a prescription because it's more powerful than retinol. Doctors prescribe tretinoin to treat skin conditions like: Acne. Psoriasis.
In the United States, tretinoin is only available with a prescription and can't be purchased over the counter. This means that you'll need to talk to a healthcare provider if you're interested in using tretinoin as an acne or anti-aging treatment.
Once your skin has fully adjusted to high-concentration retinol products, you should be able to transition to the gentlest tretinoin without much irritation or peeling. When your Retin-A prescription no longer causes unwanted reactions, consider talking to your board-certified dermatologist about a stronger one.
Tretinoin strength studies
While both were equally effective over a one year period, Tretinoin 0.1% was able to achieve cosmetic improvement in 6 months while 0.05% required closer to 12 months. Finally, 0.025% was compared to 0.1% and it was found that both produced similar improvements in photoaging.
1% tretinoin, or one unit of tretinoin per 100 units. The weakest cream contains . 005% tretinoin, or approximately 5% as much tretinoin as the strongest . 1% cream.
Additionally, Retin-A comes in a variety of strengths such as 0.25% (the lowest), 0.5% and 1.0 % (the strongest). You'll definitely want to start using the lowest dose once or twice a week.