Retin-A (tretinoin) Cream and Gel and Differin (adapalene) are retinoids (a form of vitamin A) used for the topical treatment of acne vulgaris. Differin is available over-the-counter (OTC).
A little bit of Differin gel each day goes a long way. Skin care products with retinol are found everywhere, but Differin is the lone retinoid available without a prescription. Compared to retinols, retinoids are the stronger, fast-acting sister product, explained Dr.
Differin 0.1% Adapalene Gel, for example, can help treat acne. Studies have found evidence to suggest adapalene is just as effective as stronger retinoids, but the skin tends to tolerate it better.
Treclin, however, is a medicinal gel containing two active ingredients: a 0.025% concentration of tretinoin, and a 1% concentration of clindamycin (a strong antibiotic). Though it's also aimed at moderate acne, it's certainly a stronger treatment than Differin.
Besides tretinoin, other topical retinoids include Tazorac (tazarotene) and Differin (adapalene). Differin is more aptly described as a retinoid-like compound, to be precise, but works the same way.
Differin is available OTC, classified as a retinoid and is FDA approved for the treatment of acne. In addition to treating acne, retinoids increase collagen production, which reduce fine lines and wrinkles.
Adapalene is an addition to the arsenal of topical retinoids. It possesses the biological properties of tretinoin, but has a distinct physiochemical profile, including high lipophilicity and increased chemical and photostability.
In conclusion, tretinoin and adapalene contributed to the wound healing process resulting in an enhancement of collagen production, angiogenesis and granulation tissue formation.
If you have mild or moderate acne, both tretinoin and adapalene are likely to produce a lasting, significant improvement if used consistently. On the whole, studies comparing tretinoin and adapalene typically find that tretinoin is slightly more effective as an acne treatment.
If your acne has left scarring and redness, Differin Gel may help promote a more even skin tone and decrease the appearance of scars. As a 2006 study pointed out, Differin Gel is a good option for people who have had acne and are looking for a product that will help prevent future acne.
Adapalene is a third-generation topical retinoid primarily used in the treatment of mild-moderate acne, and is also sometimes used off-label to treat aging as well as other skin conditions. It is effective for the treatment of mild to moderate acne where comedones, papules and pustules predominate.
Conclusion: Adapalene 0.3% gel showed non-inferior efficacy to tretinoin 0.05% cream as treatment for photoaged skin, with a similar safety profile. Adapalene 0.3% gel may therefore be considered a safe and effective option for the treatment of mild or moderate photoaging.
You will get an effective acne treatment with both adapalene and Tretinoin but will probably see faster improvement with Tretinoin. Everyone's skin is different, so you might see different results.
Retin-A (tretinoin) Cream and Gel and Differin (adapalene) are retinoids (a form of vitamin A) used for the topical treatment of acne vulgaris.
Studies have also shown that niacinamide reduces the irritation of retinoids, (7) so it's a good companion to have should you decide to try differin.
Try a vitamin C or vitamin E product (both of these are safe to use at the same time as adapalene).
It's also the first and only OTC acne product containing a full prescription-strength retinoid (a strong acne fighter). Are there any other strengths of prescription Differin? Yes. Differin gel is also available in a 0.3% strength.
Differin Dark Spot Correcting Serum helps to lighten post-acne marks, hyperpigmentation, blotches, age spots, and even freckles. When used every day it can improve overall skin tone and clarity.
Absolutely not. It's a common, temporary reaction that will usually subside after about 4 weeks of use. Use of Differin Gel should not be discontinued, but be sure to always use it just once daily. Try a gentle, non-comedogenic moisturizer, like Differin Soothing Moisturizer, to help manage irritation.
First, the answer is yes, retinol can make wrinkles worse, especially when you first start using it. What is happening is a drying effect, and one can get epidermal sliding from separation from the dermis.
The active ingredient is adapalene, which helps decrease swelling and inflammation, prevent breakouts, and treat scarring. According to Garshick, “it can help discoloration and textural changes that go along with acne scars by evening out the skin tone and boosting collagen production.”
For the purposes of skin care, tretinoin can be thought of as a more concentrated version of retinol. This means that tretinoin is stronger than retinol. This difference in strength can help guide your decision-making when it comes to choosing a skin care product. Your skin is affected by more than what you put on it.
Differin Dark spot correcting serum helps to lighten post-acne marks, hyperpigmentation, blotches, age spots, and even freckles. When used every day It can improve overall skin tone and clarity.
The brand of adapalene gel called Epiduo® can cause bleaching. If you have been supplied with this gel, try to avoid it coming into contact with items that could be bleached, such as hair and dyed fabrics.
Adapalene is a lower-strength retinoid, which has been available in OTC preparations since 2015. Adapalene and other retinoids reduce sebum production, follicular hyperkeratosis and inflammation.