Alopecia areata (AA) is an organ‐specific autoimmune disorder. Defective immune system related disorders are prone to increase the risk of cancer formation. However, the association among AA and variety of cancer types had never been studied.
While the disease is not medically serious, it can impact people psychologically. Support groups are available to help people with alopecia areata deal with the psychological effects of the condition. Further information may be found at the National Alopecia Areata Foundation (www.naaf.org).
Many of the genes they have found are important for the functioning of the immune system. People with certain autoimmune diseases, such as psoriasis, thyroid disease, or vitiligo, are more likely to get alopecia areata, as are those with allergic conditions such as hay fever.
Alopecia areata is an autoimmune disease. This means that your immune system mistakenly attacks a part of your body. When you have alopecia areata, cells in your immune system surround and attack your hair follicles (the part of your body that makes hair).
Alopecia areata is sometimes triggered by viral infections such as influenza that causes excess production of interferons (IFN). IFN- γ is one of the key factors that lead to the collapse of immune privilege.
Most people know alopecia to be a form of hair loss. However, what they don't always know is that there are three main types of the condition – alopecia areata, alopecia totalis and alopecia universalis.
Hair loss (alopecia) can affect just your scalp or your entire body, and it can be temporary or permanent. It can be the result of heredity, hormonal changes, medical conditions or a normal part of aging. Anyone can lose hair on their head, but it's more common in men.
This type of baldness is not usually caused by a disease. It is related to aging, heredity, and changes in the hormone testosterone. Inherited, or pattern baldness, affects many more men than women. Male pattern baldness can occur at any time after puberty.
Androgenic alopecia (AGA) is associated with significant cardiovascular risk factors that also have a negative impact on brain aging.
Alopecia areata can occur at any age but about half of cases come on in childhood and 80% of cases come on before the age of 40 years. Men and women are equally affected. The condition tends to be milder if it comes on at an older age.
There is no cure for AA. While treatments may promote hair growth, new patches of hair loss may continue to appear. The treatments are not a cure. Only the body, itself, can eventually turn off the condition.
“There are some that still consider it a cosmetic problem. It's not.” It's this stigma, along with the fact that alopecia doesn't actually shorten a patient's life span, that's kept it low on the list of priority diseases for research.
Alopecia areata (AA), an autoimmune disease that causes hair loss, including baldness, has been linked to a significantly increased risk for dementia, new research shows.
A variety of factors are thought to cause alopecia areata (al-o-PEE-she-uh ar-e-A-tuh), possibly including severe stress. With alopecia areata, the body's immune system attacks the hair follicles — causing hair loss.
Background: Alopecia areata (AA) is associated with multiple comorbidities and shares a similar inflammatory signature with dementia. The great negative psychosocial impact of AA may result in poor social engagement, a typical risk factor for dementia.
Ways to Stop Alopecia Areata from Spreading or Worsening
Avoiding unnecessary hair or scalp trauma, reducing stress and analyzing your diet are all worthwhile endeavors when attempting to prevent alopecia areata from spreading.
Female-pattern baldness is a pattern of hair loss (alopecia) caused by hormones, aging and genetics. Unlike male-pattern baldness, female-pattern baldness is an over-all thinning which maintains the normal hairline.
There is currently no cure for alopecia areata, although there are some forms of treatment that can be suggested by doctors to help hair re-grow more quickly. The most common form of alopecia areata treatment is the use of corticosteroids, powerful anti-inflammatory drugs that can suppress the immune system.
The condition can develop at any age, although most people develop alopecia areata for the first time before the age of 30. Alopecia areata is not life-threatening and does not cause physical pain.
Your diet may be the culprit. Hair loss is often caused by genetic factors. Androgenic alopecia, also called male or female pattern baldness, is a very common condition that is largely hereditary. But diet and nutrition can also contribute to increased hair loss.
If you are experiencing thinning or balding, our Bosley experts recommend washing no more than three times a week.
In its worst form, alopecia universalis causes you to lose all body hair. This includes eyebrows, eyelashes, arms, legs, underarms, pubic, and chest and back hair for men. Rarely, people who have alopecia may feel burning or itching in the areas where they once had hair.
Alopecia universalis
This is the most advanced (and rarest) form of alopecia areata. Alopecia universalis causes all of the hair on your body to fall out—including your eyebrows and eyelashes.
Compared with the general population, increased prevalence rates of psychiatric disorders are associated with alopecia (Koo et al., 1994) suggesting that people with alopecia may be at higher risk for development of a major depressive episode, anxiety disorder, social phobia or paranoid disorder.