How to improve post-inflammatory hyperpigmentation?

Author: Ernestina Lang III  |  Last update: Tuesday, July 15, 2025

How is post-inflammatory hyperpigmentation treated?
  1. Strict sun protection including the application of a broad-spectrum sunscreen containing zinc and titanium dioxide.
  2. Topical bleaching agents (such as hydroquinone, azelaic acid, tretinoin and corticosteroid creams)
  3. Chemical peels and laser therapy.

What is the fastest way to fade post-inflammatory hyperpigmentation?

Areas of hyperpigmentation might also fade on their own without treatment. To help speed up the process, there are several different types of topical medication that can reduce PIH skin spots: Skin lighteners such as hydroquinone and azelaic acid to help reduce melanin production.

How do you get rid of post-inflammatory hyperpigmented?

Azelaic acid is another medication used to treat acne and PIH. 12 It works by decreasing inflammation and speeding up cell turnover rates. People sometimes use azelaic acid along with glycolic acid or tretinoin. Some studies have shown azelaic acid to be as effective as hydroquinone at treating hyperpigmentation.

What worsens post-inflammatory hyperpigmentation?

Patients should be encouraged to avoid picking or irritating affected areas, as trauma can exacerbate postinflammatory hyperpigmentation. Sunscreen is essential, as ultraviolet exposure can worsen pigmentation and prolong healing; daily broad-spectrum sunscreen use should be a foundational part of treatment.

Can vitamin C reduce post-inflammatory hyperpigmentation?

Reducing Inflammation

Inflammation is another common cause of hyperpigmentation, especially post-acne or injury. Vitamin C's anti-inflammatory properties can help reduce redness and irritation, which prevents the formation of dark spots caused by inflammation, such as PIH.

How To Fade Acne Scars: Post Inflammatory Erythema & Post Inflammatory Hyperpigmentation

Is vitamin C or retinol better for hyperpigmentation?

The choice should come down to what you're looking to do for your skin. While vitamin C is most notable for helping to brighten and improve hyperpigmentation, retinol is typically considered best-in-class for wrinkles and fine lines.

How to remove PIH naturally?

Best home remedies for pigmentation
  1. Apple Cider Vinegar. At the top of our list, apple cider vinegar fills in the place. ...
  2. Milk. Milk has a great deal with lightening the skin tone. ...
  3. Red Onion. Next on our list of remedies is red onion. ...
  4. Aloe vera. ...
  5. Green tea extract. ...
  6. Red lentils (Masoor dal) ...
  7. Tomato paste. ...
  8. Orchid extracts.

What is the most common trigger of post inflammatory hyperpigmentation?

Common inflammatory diseases that result in postinflammatory hyperpigmentation include acne excoriée, lichen planus, systemic lupus erythematosus, chronic dermatitis, and cutaneous T-cell lymphoma, especially erythrodermic variants.

How long does it take for hyperpigmentation to go away with vitamin C?

Vitamin C can help reduce hyperpigmentation and even out skin tone, with noticeable results in as little as 3-4 weeks.

What is the best active for post inflammatory hyperpigmentation?

Topical therapies
  • Hydroquinone. Topical HQ is regarded as the gold standard for the treatment of facial hyperpigmentation. ...
  • Retinoids. ...
  • Azelaic acid. ...
  • Kojic acid. ...
  • Tranexamic acid. ...
  • Cysteamine. ...
  • Cosmeceuticals.

Why is my PIH not going away?

More severe and deep pigmentation, particularly on darker skin tones is most stubborn and may take years, to fade without proper treatment. The duration can also be prolonged further due to factors like continuous sun exposure, inflammation or injury to the skin.

Why is my post-inflammatory hyperpigmentation getting darker?

Postinflammatory hyperpigmented patches are located at the site of the original disease after it has healed. The lesions range from light brown to black in colour. The patches may become darker if exposed to sunlight (UV rays).

Why is azelaic acid making my skin darker?

This occurs because azelaic acid can inhibit the production of melanin, the pigment responsible for skin color. While this can be beneficial for treating hyperpigmentation and dark spots, it may cause uneven skin tone if not monitored carefully.

Does pie go away on its own?

Yes, PIE can fade naturally over time, but it may take several months to years depending on its severity and how well the skin is cared for. Treatment can accelerate the healing process.

What is the first line treatment for post inflammatory hyperpigmentation?

First-line therapy typically consists of topical depigmenting agents in addition to photoprotection including a sunscreen. Topical tyrosinase inhibitors, such as hydroquinone, azelaic acid, kojic acid, arbutin, and certain licorice extracts, can effectively lighten areas of hypermelanosis.

Is vitamin E or C better for hyperpigmentation?

Vitamin C is great for all skin types, especially people who experience hyperpigmentation. Because it is unstable, it is typically paired with vitamin E when creating topical skincare formulations. This combination of vitamin C and vitamin E limits chronic UV damage.

What fades hyperpigmentation fast?

“Treatments containing ingredients like vitamin C, licorice root, and kojic acid help reduce hyperpigmentation by inhibiting tyrosinase, an enzyme responsible for the formation of skin-darkening melanin," says Ni'Kita Wilson, a cosmetic chemist in New York City.

Why is my face getting darker after vitamin C?

In the absence of SPF, you may notice at times that your skin is easily tanned. Either tan or your skin may have turned into a funny orange or peach-ish color. It is because Vitamin C is extremely potent but it can easily react with the air, light and heat in the environment to only make your skin appear darker.

How to remove post-inflammatory hyperpigmentation naturally?

To reduce Hyperpigmentation, you could use the below method:
  1. Mix an equal proportion of apple cider vinegar and water in a cup.
  2. Apply the mixture to the affected areas of your skin and leave for up to two to three minutes.
  3. Now, wash using lukewarm water.
  4. Repeat this twice daily to get better results.

How to tell if hyperpigmentation is dermal or epidermal?

Epidermal: Epidermal melasma has a dark brown color, a well-defined border, appears obvious under black light and sometimes responds well to treatment. Dermal: Dermal melasma has a light brown or bluish color, a blurry border, appears no differently under black light and doesn't respond well to treatment.

Does hyperpigmentation go away when you lose weight?

Treating the underlying cause of acanthosis nigricans can make the dark patches of skin fade or even disappear. This can mean stopping any medicine that's causing the problem or treating diabetes and other health conditions. Losing weight will help acanthosis nigricans fade.

What is the difference between hyperpigmentation and PIH?

PIH appears as flat spots of discoloration. These spots can be pink, red, brown, or black, depending on skin tone and the depth of the discoloration. While post-inflammatory hyperpigmentation can occur anywhere on the body, it is most commonly seen on the face and neck, especially in acne-prone individuals.

Does apple cider vinegar help with hyperpigmentation?

Many people use apple cider vinegar on the skin to try and lighten unwanted pigmentation. Apple cider vinegar contains acetic acid, which may act as a mild chemical peel in some cases.

What can permanently remove hyperpigmentation?

CO2 Laser Resurfacing is the most effective non-surgical method to improve the appearance of your skin overall and hyperpigmentation specifically. It uses highly specialized lasers to remove dead and damaged skin cells and stimulate collagen production.

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