Treatment for post-inflammatory hyperpigmentation often involves more than one method. Your doctor might suggest a combination therapy that includes a topical steroid, a retinoid, and hydroquinone.
In general, PIH that affects only the epidermis (the top skin layer) disappears or fades significantly on its own within six to 12 months, while dermal hyperpigmentation may take considerably longer to fade and disappear, or it may be permanent.
“Treatments containing ingredients like vitamin C, licorice root, and kojic acid help reduce hyperpigmentation by inhibiting tyrosinase, an enzyme responsible for the formation of skin-darkening melanin," says Ni'Kita Wilson, a cosmetic chemist in New York City.
Medication Summary
Topical treatments include hydroquinone, azelaic acid, corticosteroids, tretinoin cream, GA, and trichloroacetic acid. Skin whitening products are used for clinical treatment of postinflammatory hyperpigmentation.
Patients should be encouraged to avoid picking or irritating affected areas, as trauma can exacerbate postinflammatory hyperpigmentation. Sunscreen is essential, as ultraviolet exposure can worsen pigmentation and prolong healing; daily broad-spectrum sunscreen use should be a foundational part of treatment.
Alpha arbutin helps reduce melanin production, fade existing dark spots and prevent new ones from forming, making it a highly effective ingredient for addressing pigmentation issues. You can also use other face serums like azelaic acid, and vitamin C for pigmentation.
Retinoids are useful in the treatment of hyperpigmentation because they reduce epidermal melanin by blocking the transcription of tyrosinase, induce desquamation, disperse keratinocyte pigment granules and enhance epidermal cell turnover via epidermopoiesis.
Common inflammatory diseases that result in postinflammatory hyperpigmentation include acne excoriée, lichen planus, systemic lupus erythematosus, chronic dermatitis, and cutaneous T-cell lymphoma, especially erythrodermic variants.
More severe and deep pigmentation, particularly on darker skin tones is most stubborn and may take years, to fade without proper treatment. The duration can also be prolonged further due to factors like continuous sun exposure, inflammation or injury to the skin.
Azelaic Acid
12 It works by decreasing inflammation and speeding up cell turnover rates. People sometimes use azelaic acid along with glycolic acid or tretinoin. Some studies have shown azelaic acid to be as effective as hydroquinone at treating hyperpigmentation.
There are also some treatments that can help PIH go away faster, like creams or lotions with ingredients like hydroquinone, retinoids, azelaic acid, glycolic acid, or kojic acid. Some procedures like microdermabrasion and light chemical peels can also help.
Reason #1: You're Getting Too Much Sun
“Hyperpigmentation can be incredibly frustrating and tough to treat. One of the easiest things you can do at home to help with hyperpigmentation is to be vigilant with sun protection,” says Dr. Camille Howard, a board-certified dermatologist and IT Cosmetics Advisory Board Member.
This can mean stopping any medicine that's causing the problem or treating diabetes and other health conditions. Losing weight will help acanthosis nigricans fade. If you're concerned about your weight, talk to your doctor before going on a diet. Doctors may prescribe creams or lotions that can help lighten the skin.
your skin, tongue or lips turn blue, grey or pale (if you have black or brown skin, this may be easier to see on the palms of your hands or soles of your feet) you suddenly become very confused, drowsy or dizzy. someone faints and cannot be woken up.
Both ingredients can fade hyperpigmentation and increase collagen production. Vitamin C (depending on the percentage) can be more harsh for sensitive skin types. Or, you might want to use niacinamide if you have acne-prone skin, and leverage Vitamin C for fading post-acne marks and dark spots.
CO2 Laser Resurfacing is the most effective non-surgical method to improve the appearance of your skin overall and hyperpigmentation specifically. It uses highly specialized lasers to remove dead and damaged skin cells and stimulate collagen production.
Tretinoin can also help fade post-inflammatory hyperpigmentation that often accompanies acne scars. Post-inflammatory hyperpigmentation is the darkening of the skin at the site of previous acne lesions. Tretinoin can promote a more even skin tone3 4 .
The choice should come down to what you're looking to do for your skin. While vitamin C is most notable for helping to brighten and improve hyperpigmentation, retinol is typically considered best-in-class for wrinkles and fine lines.
For those looking to reduce pigmentation on the face, our vitamin C serum is expertly formulated to help visibly reduce hyperpigmentation. Our CeraVe Skin Renewing Vitamin C Serum for Anti-Ageing is enriched with 10% pure vitamin C to visibly brighten and even out your skin tone.
It can be caused by a variety of factors, from pregnancy hormones and birth control pills to acne and sun exposure. Depending upon the cause of your hyperpigmentation, it may eventually go away on its own, but melasma—the type that's caused by hormones—is the most stubborn.