The amount of sebum can be reduced by certain systemic medications: Oestrogens (eg combined oral contraceptive pill) Antiandrogens such as cyproterone acetate and spironolactone. Vitamin-A derivatives such as isotretinoin.
The main cause of an overproduction of sebum is hormonal imbalances, including as a result of puberty and pregnancy. “As well as hormones, heat, exercise and genetics play a part,” says Kate Kerr, acclaimed clinical facialist.
Not Getting Enough B Vitamins
What you eat does affect every inch of your body, right down to the ends of your hair. According to HealWithFood, a person's B vitamin intake directly affects a person's level of sebum (oil) production.
An overproduction of sebum can lead to oily skin. People with oily skin may notice that their pores look larger, and their skin appears greasy or shiny. Excess sebum combined with dead skin cells can form a plug inside the pore, resulting in blackheads and pimples.
Isotretinoin. Also known as 13-cis retinoic acid, isotretinoin is an oral retinoid that has been proven to result in the greatest reduction of sebum among all other mentioned treatment options.
Vitamin B5
According to Dr. Dach, “Vitamin B5 works by reducing the oil production of the sebaceous glands.” Dach also recommends using L-Carnitine in conjunction with pantothenic acid, which can boost its effects.
Vitamin D. Vitamin D is a fat-soluble vitamin that works alongside our sebaceous glands to regulate sebum production. Vitamin D helps our bodies protect against insulin resistance which can lead to oily skin as insulin stimulates the overproduction of sebum.
Sebum production starts to decrease by age 20 and continues to slow with age. The face, scalp, upper neck, and chest host the most sebaceous glands, so when there's a surge in sebum production, these areas are prone to acne breakouts or oily skin.
In elderly men, sebum levels remain essentially unchanged from those of younger adults until the age of 80. In women, sebaceous secretion decreases gradually after menopause and shows no significant change after the 7th decade.
Sebaceous glands produce less oil as you age. Men experience a minimal decrease, most often after the age of 80. Women gradually produce less oil beginning after menopause. This can make it harder to keep the skin moist, resulting in dryness and itchiness.