Does tretinoin cause weight gain?

Author: Leonor Olson Sr.  |  Last update: Friday, April 25, 2025

If you experience any of the following symptoms, call your doctor immediately: fever; weight gain; swelling of the arms, hands, feet, ankles, or lower legs; shortness of breath; labored breathing; wheezing; chest pain; or cough.

Does topical tretinoin make you gain weight?

Retinoic Acid-APL Syndrome: Patients treated with tretinoin have experienced retinoic acid-APL (RA-APL) syndrome characterized by fever, dyspnea, acute respiratory distress, weight gain, radiographic pulmonary infiltrates, pleural and pericardial effusions, edema, and hepatic, renal, and multi-organ failure.

What is the downside of tretinoin?

The skin will be more prone to sunburn, dryness, or irritation, especially during the first 2 or 3 weeks. However, you should not stop using this medicine unless the skin irritation becomes too severe.

Does tretinoin make skin puffy?

Topical tretinoin can cause your skin to become dry, red, swollen, blistered, or flaky. It may also cause your skin to itch, be painful, or feel like it is burning.

Does tretinoin thicken or thin skin?

Topical tretinoin stimulates epidermal proliferation and differentiation by upregulating heparin binding epidermal growth factor (HB-EGF), which causes increased exfoliation and thickening of the epidermis.

TRETINOIN - The GOAT of Skincare Ingredients?

Does tretinoin plump your face?

Tretinoin is a prescription retinoid that increases cell turnover and boosts collagen production. This thickens and plumps the skin, reducing the crepey look.

Does retinol mess with hormones?

When retinol is used, it interacts with the hormone thyroxine and transthyretin. Thyroxine is produced in the thyroid gland and secreted into the bloodstream. Together, 5 Page 7 thyroxine and transthyretin form a complex that prevents the retinol binding protein from going to the kidney.

Does tretinoin bloat your face?

What side effects may I notice from receiving this medication? Side effects that you should report to your care team as soon as possible: Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat. Burning, itching, crusting, or peeling of treated skin.

Does tretinoin get rid of saggy skin?

Because it aids in boosting collagen production, studies have shown that it will strengthen your skin's elasticity to target fine lines, firm sagging skin, and smooth out uneven texture.

Is topical tretinoin bad for the liver?

Retinoids have been implicated in causing mild-to-moderate elevations in routine liver tests, but these elevations are usually asymptomatic and transient, resolving spontaneously even with continued therapy.

Does tretinoin affect hair growth?

In conclusion, tretinoin has shown promise in promoting hair growth due to its ability to stimulate cell growth and enhance blood supply to hair follicles. While many have reported positive outcomes, it's essential to consult with a dermatologist to determine if it's the right option for you.

What does tretinoin purge look like?

Skin purging is common, but doesn't necessarily happen to everyone. In fact some people don't experience it at all. For those of us who do suffer from purging, it can look like: breaking out in pustules (pimples), the appearance of flaky, peeling skin, irritation and dry patches.

Is it OK to use tretinoin forever?

Dr. Mohta says that tretinoin can be used long term, even your entire life, as tretinoin is commonly used for the treatment of acne, fine lines, wrinkles, and hyperpigmentation. Dr. Mohta, also says that it may be necessary to use tretinoin for a few weeks before you can notice changes in your skin.

Does tretinoin increase facial hair in females?

Dr Kiran acknowledges some evidence that suggests tretinoin may aid in hair growth: Tretinoin promotes cell turnover, which can help rejuvenate hair follicles. It may enhance the absorption of other hair growth treatments, such as minoxidil.

What to avoid while using tretinoin?

Avoid other topical retinoids, and skin care products containing retinol, with tretinoin. You may also want to avoid salicylic acid, glycolic acid, and erythromycin gel (Erthygel), as these ingredients and products can cause dryness.

How long does it take for tretinoin to tighten skin?

Retin-A (tretinoin) is a topical medication that's effective for the treatment of acne, wrinkles, and skin damage from the sun. It starts working within the first few weeks of treatment for acne, but can take 3 to 6 months for wrinkles.

Does Hailey Bieber use tretinoin?

Tretinoin, of course! Tretinoin helps prevent acne breakouts, improves fine lines & wrinkles and can help treat early pre cancers (actinic keratoses).

Does Nicole Kidman use tretinoin?

Neutrogena® Rapid Wrinkle Repair Regenerating Cream

Speaking to Hello Giggles, Nicole Kidman confirmed that she is no retinol sceptic — “I believe in retinol, I do think it works,” she said.

Can tretinoin tighten jawline?

After 6-9 months of regular Tretinoin use, you may notice firmer, less saggy skin around the eyes and jawline and fewer wrinkles. Be sure to use a good sunscreen every day (SPF 30 or higher) when using Retin A.

Is tretinoin 3 times A week enough?

When you first start using tretinoin, you may start with a lower percentage that you apply just two or three times a week. After two weeks, if your skin is adjusting well to the tretinoin, you can consider increasing use to every night as tolerated.

Why do I get puffy after retinol?

However, if applied too close to the eyes or in excessive amounts, it can potentially cause irritation, leading to temporary puffiness. Myth 4: Retinol makes the under-eye area more sensitive to light.

What are the negative long-term effects of tretinoin?

What harm does Tretinoin do to the skin?
  • It makes the skin significantly more vulnerable to UV damage.
  • It causes contact irritant and photosensitivity reactions.
  • It damages the skin's barrier.
  • It increases chronic inflammation which in turn disrupts barrier function.
  • Its use in one study has been linked to premature death.

Is retinol bad for your thyroid?

Thyroid hormone synthesis: Retinoids may affect the synthesis or release of thyroid hormones from the thyroid gland. Peripheral conversion: Retinoids might influence the peripheral conversion of T4 to T3, affecting overall thyroid hormone levels.

What moisturizer goes well with tretinoin?

Three inexpensive moisturizers that our physicians love are Vanicream Daily Facial Lotion with Hyaluronic Acid, Neutrogena Hydroboost Gel, and The Ordinary Hyaluronic Acid Serum. All three of these are affordable, non-comedogenic,and blend well with tretinoin.

What is the retinol purge?

Retinol purging is a temporary reaction where increased cell turnover brings underlying impurities to the surface, leading to breakouts, dryness, and irritation. Symptoms include flaking, redness, and rough texture. Although unsettling, this phase indicates that retinol is working to renew your skin.

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