First-time retinol users have reported irritation, including redness, dryness, and peeling. If you use too high a strength or apply retinol more frequently than you should, you may experience further irritation, like itchiness and scaly patches.
Chronic toxicities from long term therapy with retinoids may result in skeletal abnormalities, usually mimicking diffuse idiopathic hyperostosis syndrome. Furthermore, the chronic use of retinoids in children may inhibit their growth due to premature epiphyseal closure.
Using any form of retinol makes your skin more prone to sunburn. Sun damage combined with retinol burn is a recipe for redness or discoloration, inflammation, and more.
For adults, 19 and older, the tolerable upper limit for vitamin A is 10,000 IU per day. Talk to your doctor before taking any dose close to that amount. People who have liver disease or diabetes should not take vitamin A supplements without their doctor's supervision.
Retinoids work best if you use them daily. Specifically, they should be used at night because some types are deactivated by light and air. It's important to start slowly and allow your skin time to adjust. Using too much too quickly can cause redness, dryness, and irritation.
Should you use retinol under your eyes? Yes, definitely. While it is true that retinol – a form of vitamin A – is a powerful ingredient and the skin under your eyes is delicate, there's no reason why you should miss out on the amazing benefits of retinol.
Rouleau says the best time to use a scrub is in the morning. Overnight you've loosened up dead skin cells with your glycolic acid or retinol products, making the morning a perfect time to brush them off.
“If you're overusing your retinol, or if you're using a retinol that's too strong for you, it can lead to peeling, irritation, and excessive dryness, which may have led to retinol's association with skin thinning,” she says.
Elevated levels of serum retinol-binding protein 4 (RBP4) contribute to insulin resistance and correlate with increased prevalence of hypertension and myocardial infarction.
Begin in Your Mid 20s or Early 30s
"Your mid-twenties are a great time to start using retinol," says Ellen Marmur, M.D. "Many patients who have used it for years swear by it."
Contrary to some beliefs, retinol is perfectly safe to use on your skin.
First, the answer is yes, retinol can make wrinkles worse, especially when you first start using it. What is happening is a drying effect, and one can get epidermal sliding from separation from the dermis.
Retinol significantly decreased both hormone levels, however retinoic acid decreased the progesterone level only. In the second part of the experiments adolescent rats (in the 6th and 7th week after birth) were treated and measured similar to the newborns.
Again, there is no definitive evidence that topical retinoids lead to cancer or reproductive toxicity, but the evidence we do have is pretty much on par with that of parabens.
Cons of Retinol
Most results are not seen until 6 months or longer. Skin irritation. The side effects of retinol can include skin irritation like redness, dryness, and peeling. These can be reduced by using retinol less often or by using it with niacinamide.
Retinoids reduce fine lines and wrinkles by increasing the production of collagen. They also stimulate the production of new blood vessels in the skin, which improves skin color. Additional benefits include fading age spots and softening rough patches of skin.
Retinol and Benzoyl Peroxide
It is useless to use benzoyl peroxide, which is usually used to treat acne, and retinol together, says Paviol. The ingredients can cancel the positive effects of each other out and leave skin extremely dry and irritated.
The most common adverse effect of topical retinoids is skin irritation, notably erythema and peeling. The most severe adverse effect of systemic retinoids is teratogenicity. Each year, in the US alone over 60,000 cases of Vitamin toxicity are reported.
Pending potency, OTC retinol can take up to six months to see results." That's not to say you won't see any benefits upon the first few uses. Nussbaum explains that in the short term, the benefits are that your skin will be exfoliated of dead skin cells and your pores will be unclogged.
Retinol improves signs of aging, and vitamin E repairs and protects from photodamage. What it's for: Fine lines and wrinkles, breakouts. Celebrity fans: Victoria Beckham, Laura Harrier, Rosie Huntington-Whiteley.
A formula with retinol, like the L'Oréal Paris Revitalift Triple Power Eye Treatment, should be applied after your serums and before moisturizer due to its consistency.
Retinol (leave to absorb for 10-20 minutes)
Retinol is also an ingredient that should be left to absorb sufficiently into the skin before following up with another product. “It is important to leave a 10-20 minute wait time before applying the next product.
Use Exfoliants Sparingly After the Adjustment Period
After two to six weeks of using tretinoin, it's usually okay to start using an exfoliant. However, it's best to use exfoliating products as sparingly as possible while using tretinoin to avoid potentially irritating your skin.
Apply topical retinoids
Retinoids, which are topical vitamin A-based derivatives, may help reduce fine lines and wrinkles by increasing collagen production. If you use retinoids on your face, extend the treatment area to your neck and chest at night. Retinoid products are available by prescription or over the counter.
A number of side effects to retinoid treatment have been recorded; one group of such side effects relates to eyes and vision. Dry eye syndrome and blepharoconjunctivitis are the most common side effects, appearing in 20-50 % of patients treated with retinoids.