These unwanted effects — particularly skin dryness and acne breakouts — are widely referred to as the “tretinoin purge.” While they don't affect everyone, many tretinoin users experience some degree of purge effects during the first several weeks of treatment.
In the first two weeks, your skin's oiliness will start to decrease. Before your first month of treatment ends, you may experience the “Accutane purge.” Skin purging looks like acne exacerbation.
Generally speaking, dermatologists say purging should be over within four to six weeks of starting a new skin care regimen. If your purge lasts longer than six weeks, consult your dermatologist. It could be that you need to adjust the dosage and/or frequency of application.
Accutane "cures" about half of those people who take it so that they never need to do anything else for acne. In the first few weeks of treatment, about one in five patients gets a little worse, and one in 500 patients gets much worse. The rest either get much better, or better for a while.
Isotretinoin works by reducing the production of oil on your skin, slowing down the growth of skin cells that may clog pores and killing the bacteria in your pores that cause inflammation. Dosing is important to achieve success, and when used properly, Accutane has a nearly 90% success rate.
The results are where Accutane® treatment really shines. Peak effect is visible at the 8-12 week mark, and patients see a difference in their skin within 2 weeks. ZENA Medical is so confident in your Accutane® protocol that we guarantee your face will be 100% pimple-free after 3 months of Accutane® therapy.
Purging is a sign that the product is working and you should continue with the treatment as prescribed. After a few weeks of purging, your skin and acne will have noticeably improved. Breaking out is when your skin is reacting because it is sensitive to something in the new product.
Skin purging typically looks like tiny red bumps on the skin that are painful to touch. They are often accompanied by whiteheads or blackheads. It can also cause your skin to become flaky. The flare ups caused by purging have a shorter lifespan than a breakout.
Take with food: Isotretinoin absorbs twice as well if you take it with meals. Isotretinoin is a lipophilic medication. One study showed 1.5-2 times greater absorption in the fed (large breakfast with 28 grams of fat) versus a fasting state. This difference in absorption is not a trivial concern.
Unfortunately, when you first start using it, your acne may get worse before it gets better. Some of the more common side effects include dry skin and chapped lips. You may also have dry nasal passages, which can make your nose bleed.
Accutane Side Effects:
Before your acne can get better, it will likely get worse at the beginning stages of taking Accutane. Called purging, the drug will push out all dead skin cells, oil, and debris from underneath the skin causing inflammation and more acne. Once this stage is complete, acne will begin to subside.
During the first 3 weeks you are taking isotretinoin, your skin may become irritated. Also, your acne may seem to get worse before it gets better. Check with your doctor if your skin condition does not improve within 1 to 2 months after starting this medicine or at any time your skin irritation becomes severe.
Most patients don't see an appreciable difference until the third month of treatment. But first comes the “purge,” when all the old skin cells start rising—at an accelerated rate, with a potent retinoid—from the bottom layer of the epidermis up to the surface. “It gets worse before it gets better” is the adage.
Use of isotretinoin should be considered in mild to moderate acne also, in low doses; 20 mg, alternate day seems to be an effective and safe treatment option in such cases.
While you are taking Accutane and for at least 6 months after your last dose: Do not use wax hair removers or have dermabrasion or laser skin treatments. Scarring may result. Isotretinoin could make you sunburn more easily. Avoid sunlight or tanning beds.
These unwanted effects — particularly skin dryness and acne breakouts — are widely referred to as the “tretinoin purge.” While they don't affect everyone, many tretinoin users experience some degree of purge effects during the first several weeks of treatment.
A purge can last as long as two months, and you should start seeing an improvement by the six-week point, if not sooner. On the other side of a purge is cleaner, clearer skin!
Purging pimples do not leave marks or blemishes on your skin. It actually heals the skin to form fresher skin cells. Breakouts don't benefit the skin; they leave marks and blemishes when they go. The cell turnover is faster to remove dead cells.
“Purging is neither good nor bad. It can happen after using excellent products but, equally, it also frequently occurs when the skin barrier is compromised prior to starting with a product or treatment.
When it comes to treating your skin during a purge, the best thing that you can do is actually the least satisfying answer anyone really wants to hear—you just have to wait it out. “Depending on how congested your skin is, a purge can last from two to three weeks,” Dr. Linkner states.
Hormonal acne is more likely to come back after a course of Roaccutane (Accutane) has successfully cleared it. Besides being stubborn to treat, hormonal acne causes redness for prolonged periods, scarring and pigmentation.
While you are taking Accutane, the medication actually shrinks oil glands and dries out the skin. But when you stop taking it, your pores will return to their original size. Chemical peels can improve the skin's texture and minimize the appearance of pores by peeling off the old layer of skin.
Zenovia: After getting off Accutane, it's very important to continue being diligent about skin care. Incorporating an effective spot treatment, lightweight moisturizer, sunscreen, and retinol into your routine will help keep the skin balanced and healthy.