In clinical studies, the line-smoothing effects of Daxxify — also known as Daxi — lasted an average of six months, about double that of Botox, Dysport, Jeuveau, and Xeomin. For that reason, "it's been a welcome addition to the neuromodulator community," says Dr.
However, DAXXIFY™ is the only neuromodulator that can last for up to six months on average—and sometimes even up to nine months for some patients. The reason why it's so long-lasting is because the neurotoxin is stabilized by Peptide Exchange Technology™ (PXT).
"With Daxxify, the average duration of effect is 24 weeks, so around six months." Not only is the onset of activity faster with Daxxify, but the product's effects last longer than those of the other botulinum toxins in use today.
In general, Botox lasts 3-4 months. There will certainly be patients in which in lasts longer, in that 4-6 month range, or shorter, in that 2-month range. It is also common for first-timers to notice that it may not last as long initially but may last longer after the second treatment.
DAXXIFY® may cause serious side effects, including allergic reactions (such as itching, rash, redness, swelling, wheezing, trouble breathing, or dizziness or feeling faint), heart problems (such as irregular heartbeat and heart attack), and eye problems (including dry eye, reduced blinking, and corneal problems).
It's crucial to avoid rubbing or massaging the area for at least 24 hours after your DAXXIFY injection. Strenuous exercises and heat exposure, such as saunas or sunbathing, should also be put on hold for at least 48 hours.
On a per-unit basis, the cost of Daxxify is typically more than Botox. This is because Daxxify provides significantly longer-lasting results. However, because patients only need to get 2 treatments per year with Daxxify as opposed to 4 with Botox, Daxxify may actually be the less expensive option over the long-run.
Muscle Atrophy and Adaptation: After long-term Botox use, some facial muscles may experience mild atrophy due to limited activity. This can actually benefit patients who prefer a smoother look, as muscle activity that causes wrinkles is minimized.
No. Even after you stop using BOTOX, you will still look younger than you would have if you had never been injected. One study of twins found long-term BOTOX use led to fewer and less severe wrinkles in the long run, effectively slowing the aging process.
High intensity workouts are designed to boost your metabolism in order to burn calories and build muscle more quickly. By raising your metabolic rate, you may be causing your body to metabolize the Botox more quickly so it breaks down sooner than expected.
That's up to 4-6 months of total wear off time per year! DAXXIFY is different. With those same 2 treatment visits, you can keep your frown lines smoother for a full year! At least 50% of patients in clinical studies had no or minor frown lines 6 months after treatment.
Daxxify® is slightly costlier than Dysport® treatments but can be more cost-effective in the long run. That's because most Dysport® patients may need touch-up injections every three to four months, while some patients who respond well to Daxxify® may only require two appointments annually.
Celebrities often pick alternatives like Dysport, Xeomin, and Juvederm. These fillers add volume or reduce wrinkles differently than Botox. They're popular for their varying effects and durations.
All neurotoxins need proteins to help penetrate targeted muscles and wrinkles, and Botox and Dysport use certain accessory proteins for that job. However, Daxxify is the first neuromodulator to use a unique peptide to make Daxxify longer-lasting.
DAXXIFY is longer-lasting
Studies have shown that while BOTOX injections last up to four months after one session, DAXXIFY can last 6 – 9 months in the same area. Our “BOTOX” alternative is an attractive option for individuals who may not have the time or resources to get treatments every 3 – 4 months.
“Anecdotal evidence suggests that working out and a faster metabolism may break down a neuromodulator faster. Conversely, there are patients who report that they see longer-lasting results as their metabolism slows with age.”
Long-term effects
A 2022 review study found that people who regularly received Botox injections showed changes in their muscle composition, function, and appearance up to four years after their last injection. "If you didn't use your abs [abdominal muscles] for 10 years, they would waste away," says Mosahebi.
Both Botox and dermal fillers are eventually metabolized by the body and safely excreted through the liver and kidneys.
A common concern is whether your skin will sag after you stop Botox treatments. The good news is that Botox itself does not cause sagging, nor does stopping it lead to sagging skin. However, it's important to remember that the aging process continues, regardless of whether you've had Botox or fillers in the past.
Some rare but potential risks for patients over the age of 65 include: Reactions At the Injection Site—Bruising, pain, and swelling around the injection site are the most common side effects of a Botox treatment. These reactions happen if a blood vessel is temporarily damaged during the injection process.
“Pillow face” occurs when too much filler is injected into areas like the cheeks, nasolabial folds (the lines from your nose to the corners of your mouth), lips, and under-eye area. This repeated overfilling can result in a bloated, round appearance that looks far from natural.
Yes, it does cost more than other neuromodulators like Xeomin or Botox, but Daxxify's quicker and longer-lasting results work out to be about the same in the long run for me. And because you'll see results in around two days, you might prefer Daxxify if you've got a special occasion and want smooth skin fast.
The cost for Daxxify lanm 100 units intramuscular powder for injection is around $448 for a supply of 1 powder for injection, depending on the pharmacy you visit.
In fact, clinical trials found that DAXXIFY results can last between 6-9 months, potentially lasting 2-3 times longer than BOTOX for some patients. Additionally, DAXXIFY is the first injectable neurotoxin formulated using a novel peptide as a stabilizer, meaning it does not contain human or animal byproducts.