Because you'll be moving those specific muscles less when they are under the effects of BOTOX, they may weaken to a very small degree over a long span of time. Many people actually see this side effect as a bonus: People who keep up with routine BOTOX appointments find their results last longer with regular use.
"If you do too much Botox on your forehead for many, many years, the muscles will get weaker and flatter," cautions Wexler, adding that the skin can also appear thinner and looser. Moreover, as your muscles become weaker, they can start to recruit surrounding muscles when you make facial expressions.
Botox is classified as a neuromodulator, which means it inhibits nerve transmission. When injected, it binds to your muscles at the injection site. Over one to three days, it will begin to block the release of acetylcholine, causing muscle weakness.
There are no long-term or life-threatening adverse effects related to botulinum toxin treatment for any cosmetic indications. Moreover, the risk of possible complications can be reduced by means of a thorough analysis of the patient's medical history and the use of the appropriate dose and technique for the injection.
While botulinum toxin paralyzes these muscles, the paralysis doesn't last forever. Eventually, the body breaks down the botulinum toxin and the muscles are able to move again.
It's true: Even after you stop, you will still look younger than you would have if you had never been injected. One study of twins found long-term BOTOX use led to fewer and less severe wrinkles in the long run, effectively slowing the aging process.
Botulinum toxin-induced atrophy has been reported as early as one month after injection, and is well maintained for 6 months. In some cases, variable degrees of atrophy were noted up to one year after a single administration.
He said Allergan knew that Botox could cause Guillain Barre Syndrome because the company's internal documents show they had Guillain Barre Syndrome on their list of top 3 safety concerns in February 2008, eight months before McGee was injected.
But despite this impressive track record, some people are still concerned that the botulinum-based product could pose certain health risks. In fact, there are those that wonder: Is Botox poisonous to your body? The good news is that Botox is not poisonous to the body.
According to an investigation published in the January issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS), researchers have discovered that injecting Botox (botulinum neurotoxin type A) affects muscles other than those it's injected into.
Botulinum toxin A creates muscle weakness and atrophy following long term use, study suggests. Summary: A new study found animals injected with Botulinum toxin A experienced muscle weakness and atrophy far from the site of injection.
There is no definite age when you should start BOTOX®—it's more about the state of your skin, and everyone's timeline is different. For wrinkle treatments, it's best to start when you notice forehead lines, frown lines, or crow's feet even when your expression is neutral.
An upset stomach, nausea, or constipation can occur in 1 to 10% of patients. Symptoms are reported as mild or moderate and typically last a few days up to two weeks.
What are neurotoxins? Neurotoxins, also known as Botox, Dysport, and Xeomin are injectable solutions that temporarily block nerve receptors in the muscle, preventing lines and wrinkles from forming. They can be used to treat muscle stiffness, muscle spasms, excessive sweating, and overactive bladder.
Dysport, like Botox, is a neurotoxin. It's made of the same type of bobotulinum toxin A as Botox, but has slightly different dosing technique and structure. Results seem to be about the same for both Dysport and Botox, but Dysport seems to work slightly faster.
This side effect was more common among people taking Botox to treat: cervical dystonia (involuntary tightening of neck muscles) spasticity (involuntary muscle spasms)
Be truthful about medications.
Medications like sleeping pills, blood thinners, Ginkgo biloba, vitamin E, and muscle relaxants do not mix well with Botox.
Over time, repeated injections of Botox® to a particular area in the body can also cause permanent paralysis of the muscle. This is by far one of the most important and dangerous side effects of using Botox® injections. The toxins can spread into the surrounding tissues and this can prove to be fatal.
Patients with diseases of the neuromuscular junction such as myasthenia gravis and Lambert-Eaton syndrome are particularly susceptible to adverse events of botulinum toxin.
Botox Can Trigger Immune Response
Botulinum toxin type A is a protein complex that can cause the immune system of some patients to respond by forming neutralizing antibodies that weaken the toxin's effectiveness.
Management and Treatment
Neurogenic atrophy typically can't be reversed because of the physical damage that's been done to your nerves.
The toxin injections might make the collagen in the skin “more organized”, the researchers said. Other studies have shown Botox can cause the skin to produce more collagen and elastin, which makes the skin more elastic.
“When an area of the face is frozen with absolutely no wrinkles, you can assume the person has had a date with a needle.” "When you look at a photo and see an area of the face that is extremely smooth and shiny," Rusher says, "that can be an indicator that the person may have had Botox."
MACON, Ga. -- Psychology Today reports that injections to smooth out wrinkles, like Botox and Myobloc, can rearrange the brain's sensory map of the hands. That study found ongoing treatments over a period of years could lead to permanent changes in the brain.