The truth: You can use vitamin C with retinol and retinoids. Get them as separate products so you can tailor the concentration of each and use them at the right time of day. Although vitamin C can be used day or night, it is ideal for daytime use, while retinol and retinoids should be applied at night.
It's best to apply Vitamin C before Retinol, as Vitamin C has a lower pH than Retinol. Once your skin absorbs the Vitamin C serum, your skin will return to its regular pH levels after 30 minutes or so. (You want your skin to return to its normal pH levels so vitamin C doesn't lower the pH of retinol.)
Since retinol and L-ascorbic acid have a big gap in pH, using them at the same time will lower the retinol's pH and raise the vitamin C's pH. The result? The retinol will become less active, and the vitamin C will have a reduced ability to get into your skin. Essentially, they will both become less effective!
In short: yes, you can use vitamin C and retinol together; try retinol at night and vitamin C during the day—always with sunscreen.
So, should I use vitamin C or retinol for wrinkles? Well, when it comes right down to it, the choice is really in what you're looking to do for your skin. While vitamin C is incredible for the skin because of its ability to help brighten and improve hyperpigmentation, the best active ingredient for wrinkles is retinol.
If your skin care involves nothing but using vitamin C in the morning followed by nightly applications of Retin-A, you'll have glowing, more youthful skin. (Sunscreen, of course, should also be applied daily.)
AHAs and BHAs, such as glycolic, salicylic, and lactic acids should never be used with Vitamin C. Vitamin C is an acid, too, and is unstable, so the pH balance will be thrown off by layering these ingredients together and might as well be useless.
Is it a good idea to combine Vitamin C, Retinol and Hyaluronic Acid in a skincare routine? Yes. These ingredients work well when used individually and even better when paired together.
Use your vitamin C serum first, and let it dry.
Then "Let vitamin C completely dry prior to placing niacinamide," says Lamm. That way, the ascorbic acid has a chance to settle into the skin, and there's a smaller chance of combining the two actives.
A thick moisturizer with hyaluronic acid would be applied after a vitamin C serum, but a hyaluronic acid serum will come before a face cream with vitamin C in its formula. In the case that you have two separate serums, it still comes down to thickness. Apply whichever is thinner first.
When layering these powerful ingredients applying vitamin C first and leaving about 15 minutes in between applying your niacinamide product will give the skin enough time to absorb and remain comfortable before using niacinamide to lock moisture into the skin.
“AHA, BHA, retinol, and benzoyl peroxide can be mixed with moisturizing ingredients like hyaluronic acid, ceramides, and rosehip oil to get effective results — just ensure you are not using retinol as well as AHA or BHA's during the day," says Graf.
Don't Mix: Retinol with vitamin C, benzoyl peroxide, and AHA/BHA acids. AHA and BHA acids are exfoliating, which can dry out skin and cause further irritation if your skincare routine already includes retinol.
Niacinamide and retinol can be combined in one product, which may be easier and more convenient. But they're also available as separate products. If you're using these ingredients in separate products, it's recommended to apply niacinamide first and to then follow with retinol.
First, vitamin C works to help improve the look of dark spots, fine lines, wrinkles and sagging skin. Then, retinol steps in to help improve skin's elasticity. The result is that retinol and other retinoids may help improve skin's texture while helping to minimize the look of fine lines.
Retinoids work best if you use them daily. Specifically, they should be used at night because some types are deactivated by light and air. It's important to start slowly and allow your skin time to adjust. Using too much too quickly can cause redness, dryness, and irritation.
You can absolutely use vitamin C and niacinamide together, Singh goes on to emphasize. That said, if you ever have any doubts as to whether it's safe to mix two skin care ingredients, a dermatologist can always offer advice.
In general, most people won't need to use an exfoliant with tretinoin. Instead, the best approach is to let tretinoin work on its own to speed up skin cell turnover and improve your skin, all while managing potential dryness, flaking and irritation through good hydration and moisturizing.
A formula with retinol, like the L'Oréal Paris Revitalift Triple Power Eye Treatment, should be applied after your serums and before moisturizer due to its consistency.
If you're wondering when to apply a vitamin C serum, the answer is both morning and night, after cleansing and toning. One study even recommends applying a vitamin C serum every eight hours, or twice daily for the pinnacle of protection.
The best product you can use in conjunction with retinol, according to Dr. Zeichner, is a moisturizer, which can help hydrate skin and reduce the risk of irritation from retinol. “Some people even prefer to mix their retinol with a moisturizing cream to dilute it out,” he says.
Use vitamin C for hyperpigmentation caused by melanin and use niacinamide if your skin can't handle vitamin C. Keep in mind this is a very hard and fast rule because they aren't easy to compare without really knowing your skin concerns and skin sensitivity.
Vitamin C works best in combination with Vitamin E, Ferulic Acid, Vitamin B, and Hyaluronic Acid. Designed to deliver a high concentration of actives, Vitamin C booster serums are a popular choice in skincare.
Hyaluronic Acid and Niacinamide
These water-based treatments are a great pair and are made for all skin types — especially babes with dry, acne-prone skin. You'll find niacinamide, a form of vitamin B3, in my Rewind Retinol Serum. Use hyaluronic acid first, followed by my retinol for the best results.
It's perfectly safe and okay to use hyaluronic acid and retinol together. Using skin care products that contain these ingredients together shouldn't cause any interactions or side effects. Hyaluronic acid and retinol are one of the most popular skin care combinations.