There exist cases where magnesium has been used continuously for over long periods as seen in sleep disorders, sustained eclampsia, Covid-19 and even diabetes [1,7,6]. Little or nothing is known of the adverse effect of this supplement in the gastrointestinal tract over these long period of administration.
Taking high doses of magnesium (more than 400mg) for a short time can cause diarrhoea. There's not enough evidence to say what the effects might be of taking high doses of magnesium for a long time.
Magnesium supplementation can not only preserve liver function, but also slow the progression of liver disease, and reduce the mortality associated.
Magnesium supplements are a long-term thing. They affect your life in months and years, not in days or weeks. They're not a drug that has immediate effects. Stopping it for 5 weeks is no big deal.
More common side effects from magnesium include upset stomach and diarrhea. Magnesium competes with calcium for absorption and can cause a calcium deficiency if calcium levels are already low. Some medications may lower magnesium levels in the body.
Magnesium can be a long-term supplement that you can take for years. Nevertheless, you should always check with your doctor to make sure that you're not exceeding the recommended dosage. Your doctor will run regular lab tests to make sure that your magnesium levels are within the normal range.
The benefits of magnesium supplementation in healthy individuals aren't clear, but Dr. Nassar says that taking a magnesium supplement every day likely isn't unsafe for most people. Just be sure you're not taking too much magnesium. The maximum dietary allowance for most adults is around 400 mg or less.
When taken in very large amounts (greater than 350 mg daily), magnesium is POSSIBLY UNSAFE. Large doses might cause too much magnesium to build up in the body, causing serious side effects including an irregular heartbeat, low blood pressure, confusion, slowed breathing, coma, and death.
In extreme cases, too much magnesium can cause an irregular heartbeat and cardiac arrest (when the heart stops beating). Magnesium toxicity usually only happens if you take large quantities of magnesium in the form of magnesium supplements, antacids or laxatives.
People with diabetes, intestinal disease, heart disease, or kidney disease should not take magnesium before speaking with their health care provider.
Causes. Every organ in the body, especially the heart, muscles, and kidneys, needs the mineral magnesium. It also contributes to the makeup of teeth and bones. Magnesium is needed for many functions in the body.
Mg intake may only be related to reduced odds of fatty liver disease and prediabetes in those whose Ca intake is less than 1200 mg/d. Mg intake may also only be associated with reduced odds of fatty liver disease among alcohol drinkers.
What drink increases magnesium? Juices containing plenty of whole fruits and veggies may have a good amount of magnesium. Milk has 24-27 milligrams per cup. Water from your tap as well as mineral or bottled waters also could give you a good amount of magnesium if you drink the recommended two liters a day.
If you have a mild magnesium overdose and normal kidney function, the typical treatment is simply to stop taking any magnesium supplements to give your body time to excrete the excess magnesium.
“Magnesium is generally considered safe although caution should be used in patients with kidney disease due to the risk of developing high magnesium levels.
Prescribe 20mmol magnesium in 100ml or 250ml of compatible fluid IV over 3 to 4 hours. If having IV fluids can add 20mmol magnesium to 500ml or 1L bag of compatible fluid and give IV over 3 to 24 hours.
Don't use calcium, zinc, or magnesium supplements at the same time. Also, these three minerals are easier on your tummy when you take them with food, so if your doctor recommends them, have them at different meals or snacks.
Higher intakes of Mg (OR: 0.41, 95% CI: 0.22–0.76) were significantly associated with a lower risk of CKD. The protective effect of Mg (estimated average requirement: 581 mg) decreases the risk of CKD by 60%.
Magnesium toxicity and overdose are rare. However, some people have a higher risk, including people with impaired kidney function and those taking high-dose magnesium supplements or magnesium-containing medications (such as antacids or laxatives) for long periods. You cannot overdose on magnesium from diet.
People experiencing low magnesium symptoms will have higher blood pressure, higher blood sugar, more headaches and muscle cramping, worse anxiety, and trouble sleeping. It's easy to overlook recommending magnesium, especially if lab results are within normal range.
Toxicity is rare from food sources because the kidneys will remove excess magnesium in the urine. However toxic levels may occur with long-term use of high-dosage supplements. People with kidney disease have a higher risk of toxicity because their kidneys are not working properly and cannot flush out extra magnesium.
About 50% of people worldwide have low vitamin D levels. And between 10% and 30% of the population are thought to have low levels of magnesium. For many people, it's important to take vitamin D and magnesium together. Without magnesium, your body can't use vitamin D.