Because Botox is a form of a toxin produced by a bacteria, the body can sometimes develop an immune response to the injections. This will cause the body to break down the Botox injections quickly so that they are no longer effective.
To put it plainly, Botox resistance (immunity) does occur in some patients. According to those who do recognize the phenomenon of Botox resistance, the numbers are low—about 1% to 3% of patients who are injected will develop toxin-blocking antibodies.
Reasons why Botox may not work
Botox is not a one size fits all treatment and the same dosage does not work for everyone. Some individuals may need additional Botox to reach an effective level of muscle weakness. The Botox may also be old, overdiluted, or fake.
True BOTOX resistance is fairly rare—manufacturer clinical trials showed that no more than 1.5% of patients developed any “neutralizing antibodies” to the drug. Other doctors estimate that as few as 1 patient in 10,000 has real BOTOX resistance.
Consistently high-stress levels can cause the body to break down Botox more quickly while speeding the aging process. Taking part in meditation, yoga, and other stress-relieving activities can help you maximize the life span of your Botox while reducing any stress-related aging.
Botox® injections work well as a standalone treatment for mild to moderate frown lines. However, if the 11s are deep, Botox® alone may not be enough to reduce the appearance of forehead wrinkles. For the best results with deeper 11s, dermal fillers can be used along with Botox® treatment.
Answer: Botox takes a while to work
Once the muscles stop contracting, the lines can take quite a while to disappear in some patients. If you continue to maintain the inability of the muscles to contract by having repeat Botox before the muscle wakes up ( around 3 to 4 months), the lines should continue to improve.
Botox can reduce the appearance of static wrinkles as well, but not as effectively as dynamic wrinkles. If you have static wrinkles, you should consider dermal fillers, i.e., injectables that infuse your skin with hyaluronic gel or trigger collagen production to temporarily fill the status wrinkles and fine lines.
At what age should you stop using Botox? There is no upper age limit for people who want to have Botox. In fact, many women enjoy the refreshed look they can get from Botox and complementary treatments when they are in their 60s or older.
Botox limits movement by blocking acetylcholine, the chief neurotransmitter. Over time, the theory goes, a repeat user of Botox weakens her facial muscles, slowing the process in which dynamic lines (those that form when she is making an expression) settle into static lines (those visible when her face is at rest).
There's a common misconception that Botox makes you look older when it wears off. On the contrary, regular Botox treatments make you look younger even after the neurotoxin wears off.
Ask Your Dermatologist About Microneedling, Which Can Fade Scars and Smooth Wrinkles. One of the leading skin-care trends is microneedling. “Microneedling is a less invasive procedure that can treat wrinkles and scarring,” says Ploch.
Why Does Botox Make Your Forehead Shiny? Light naturally reflects off of smooth surfaces, so the smoother your skin, the more light will bounce. Botox injections smooth the skin, which can cause it to appear shinier, especially if it is overdone.
It's rare to see cases of Botox being ineffective on the forehead especially if it was administered by a qualified and experienced provider. Despite its high efficacy rate, there are cases when Botox injections on the forehead don't produce the same results clients expect.
When some people see their wrinkles form again after the rejuvenating effects of Botox wear off, they assume that the treatment made their wrinkles worse. This isn't true at all. In fact, regular Botox use can actually retrain certain muscles to move less, leading to smoother skin with less Botox over time.
It sounds like the muscle has been knocked out with the dose you received. It will take many weeks or even months for the crease to smooth out and it is important to keep up with the Botox to keep those muscles knocked out or they will once again work on the overlying skin to reform the wrinkles.
25 Units Of Botox On Average
On average 25 units of Botox will give your skin by your glabellar a full correction and will remove the 11 lines. The '11 lines' are the glabellar lines in between your eyes and eyebrows.
"Botox binds to receptors on nerve cells to relax muscles, and it is possible that exercise speeds this binding process," Alam explained. "For patients who need quick results, the exercise may be worth the effort.
Zinc is known as a “Botox booster” based on a few studies. Zinc has been found to be effective in extending the effects of botulinum toxin injections up to 30 percent.
You can expect results to last around 4 months, but don't be surprised if you notice a long term decrease in wrinkles. The relaxation of those muscles allows them to weaken and resist movement even between treatments. If you're looking to lift the brow area, Botox can help without going under the knife.
The U.S. Food and Drug Administration (FDA) has approved Daxxify, a new injected medicine for smoothing facial wrinkles in adults, which dermatologists see as the first major competitor to Botox to emerge in decades.