While glycyl-L-histidyl-L-lysine-copper (GHK-Cu) has a variety of biological functions, it is not easily absorbed by skin directly, which along with several contraindications, greatly limit its clinical use.
Skin may be a route of entry of metals after contact with metallic items. Dermal absorption of Beryllium (Be) and Copper (Cu) may cause skin sensitization and toxicity in humans. After the deposition of eyeglass temple tips on the skin, Be and Cu can penetrate and permeate this cutaneous membrane.
Yes! In fact, we recommend it! Copper peptides work synergistically with vitamin C to trap moisture and improve the skin's texture. Try combining them with moisturizing products that are rich in a gentle form of vitamin C, such as our Vitamin C Rose Moisturizer or Vitamin C Rose Oil.
The injectable GHK-Cu suggested dosage is 0.2 mL delivered subcutaneously. This is meant to be given once per day. The topical foam is meant to be applied once each night. Around 2-3 pumps of the foam should be applied.
Copper Overload: GHK-Cu contains copper, which is an essential trace element in the body. However, excessive copper intake can lead to copper toxicity. To avoid this, it's important to use GHK-Cu products as directed and within safe concentrations.
Some people may see results within a few weeks, while it may take several months for others. It is important to be consistent with the use of GHK-Cu and to follow the recommended usage instructions.
Possible Side Effects of Copper Peptides
While copper peptides are a low-risk skincare ingredient, they can trigger an allergic reaction in some individuals. Signs of an allergic reaction include hives, itchy or burning skin, and redness. Sensitive skin types are more prone to reactions.
Prepare the Base: Add 100 ml of distilled water or hydrosol in a glass mixing bowl. Add GHK-Cu Powder: Weigh 1 gram of GHK-Cu Copper Peptide Blue Powder using a precision scale. Slowly add this to the water while constantly stirring to ensure it dissolves completely.
Anti-wrinkle peptides, like other peptides, suffer from insufficient skin permeability, while most of them must penetrate deep in the skin to present their efficacy.
So, can skincare be absorbed into the bloodstream? Most skincare formulas are designed to work on the top layers of the skin, or penetrate to slightly deeper layers, but that doesn't mean absorption into the bloodstream isn't possible, however, it's pretty unlikely.
For that reason, mixing peptides and glycolic acid is not recommended. Why shouldn't these acids be mixed with peptides? The reason peptides and salicylic acid as well as peptides and glycolic acid aren't efficacious ingredient combinations is because peptides are susceptible to hydrolysis when exposed to acids.
Regular use of copper peptides can lead to a noticeable reduction in the appearance of fine lines and wrinkles. As a result skin is left smoother and more refined. They can also enhance skin elasticity and firmness. This helps combat the sagging that often accompanies skin aging.
There is also no confirmation that people can absorb copper through the skin from a solid piece of jewelry.
Thorne Copper Bisglycinate is a well-absorbed form of copper which is essential for collagen, nerve, blood vessel, and heart health. If you are taking a high amount of zinc, you may develop a copper deficiency.
Exact directions may vary depending on the product you choose, but generally, a GHK-Cu serum should be applied directly to your dry or damp scalp once daily, massaged evenly and thoroughly, and not rinsed out. Serums are very concentrated, and you typically only need to use a drop or two at a time.
DOES GHK-CU ACTIVATE STEM CELLS? GHK-Cu has been found to influence stem cell behavior by increasing their proliferation rate while maintaining their pluripotency status. A study showed that treatment with GHK-Cu significantly increased human mesenchymal stem cell migration without affecting differentiation potential.
As a word of caution, it is generally not recommended to copper peptides with retinol and AHA/BHA, as these ingredients may reduce the overall effectiveness of copper peptides.
These placebo-controlled studies demonstrated that GHK-Cu skin creams had the following effects: Tighten loose skin and improve elasticity. Improve skin density and firmness. Reduce fine lines and deep wrinkles.
Research suggests that GHK-Cu promotes hair follicle growth, extends the hair growth phase (anagen phase), and enhances hair thickness. By providing essential nutrients and signaling molecules to the hair follicles, GHK-Cu injections hold promise as a potential treatment for various forms of alopecia.
Some skin types may be sensitive to copper, and there's a chance that overusing copper skincare products could be detrimental to your skin health. That's why I use non-copper peptides, like the ones you'll find in my Hydration Peptide Cream.
GHK-Cu does lower blood pressure, but the LD50 (Lethal Dose for 50% of mice) for such effects would be about a single dosage of 23,000 mgs of GHK-Cu in a 70 kg human.
Copper not only looks good on your skin, but do you know that it is also good for your skin: It is needed for a wide range of biological functions that play an important role in improving skin health, namely skin tone, wound healing, and ultraviolet (UV) protection.
A: As I understand it, ghk-cu is used for skin, joints, scars.... akh-cu is used for nails and hair growth. they interfere with each other, so must used separatelly. Also, any lotion they are added to must not have any form of ascorbate acid that neutralizes their potency.